Figure 4

The distribution of SNPs is drastically different between the three HSPA1 genes. Synonymous and non-synonymous SNPs were mapped along the amino acid sequence of (a) HSPA1A, (b) HSPA1B, and (c) HSPA1L using sliding window analysis. The domain organization of Hsp70s (from)61 is depicted on the top: NBD = nucleotide binding domain; SBD = substrate binding domain.