Table 3 Polymorphic sites and density for the three HSPA1 and five neighboring genes reveal that HSPA1A and HSPA1B have low mutational loads. These data are derived from the 1000-Genomes (1000 g) and ExAC datasets. (SNP Density = SNP N/Region Length).

From: Concurrent action of purifying selection and gene conversion results in extreme conservation of the major stress-inducible Hsp70 genes in mammals

Gene

Region Length (bp)

SNP sites (1000 g)

SNP sites (ExAC)

Density Ratio (ExAC/1000 g)

N

Density#

N

Density

HSPA1A

2432

39

0.016

46

0.019

1.2

HSPA1B

2519

46

0.018

83

0.033

1.8

HSPA1L

6041

153

0.025

307

0.051

2.0

VARS

18434

410

0.022

961

0.052

2.3

LSM2

9587

228

0.024

114

0.012

0.5

C6orf48

5155

160

0.031

223

0.043

1.4

NEU

5246

85

0.016

285

0.054

3.4

SLC44A4

15853

422

0.027

647

0.041

1.5