Figure 3 | Scientific Reports

Figure 3

From: Sample-Index Misassignment Impacts Tumour Exome Sequencing

Figure 3

Per-sample counts of apparently true somatic variants (a) and suspected contaminant variants (b) plotted against contamination estimates. All values, including Spearman’s rank correlation coefficients and their associated p-values, are plotted separately for each combination of tumour type and amplification chemistry represented in the analysis. The colours distinguish between “high-contamination” samples (Conpair contamination estimate >  = 0.5%) and samples with “low contamination” (Conpair contamination estimate < 0.5%). BrAmp: bridge amplification; FL: follicular lymphoma; SARC: sarcoma; DLBCL: diffuse large B-cell lymphoma.

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