Figure 3
From: Extensive molecular tinkering in the evolution of the membrane attachment mode of the Rheb GTPase
Rheb evolution in the Euglenozoa. (A) Inferred origin, loss, and modifications of Rheb paralogs in the Euglenozoa. Relationships of the taxa are based on ref.59 and ref.60; note that Flectonema neradi61 was previously referred to as Diplonema sp. 2. The placement of the two unnamed Prokinetoplastina species is based on an unpublished phylogenomic analysis (Tikhonenkov et al. in preparation). The Euglenophyceae comprise Euglena spp. and Eutreptiella cf. gymnastica. (B) Maximum likelihood phylogenetic tree (RAxML-HPC2, LG4X + Γ substitution model) of Rheb proteins in the Euglenozoa and relatives. Support values at branches correspond bootstrap values (>50%) from the ML analysis and to posterior probabilities (>0.9) from an analysis by MrBayes. Sequence identifiers are provided in Supplementary Table S1.
