Figure 5

Afterdischarge burst frequencies are not affected by inhibition of contralateral hippocampus. (a,b) 10 s post-stimulation periods immediately preceding CNO injection (a) and 10 stimulations post CNO injection (b), with details of ipsilateral bursts at the top (same animal as in Fig. 4g). Recording traces were Fast Fourier Transformed to examine burst frequencies (bottom). AD burst power was concentrated to frequency ranges of 15–30 Hz and 60–90 Hz in both groups. (c) Quantification of the burst frequencies on group level, taking the mean of the median burst frequency for each animal. There was no difference between groups (one way ANOVA), or from pre- to post-injection within groups (paired t-test), either ipsilateral or contralateral (see Results for P values). Scale bars (a & b): box: 5 mV, 50 ms; 5 mV, 1 s. Error bars: ± SD.