Table 2 Differences between groups for plasma markers of Notch pathway after controlling for age and gender.

From: Attenuated Notch signaling in schizophrenia and bipolar disorder

plasma ligands

M(IQR)

SCZ vs. HC

BD vs. HC

SCZ vs. BD

SCZ

BD

HC

df

t

F

df

t

F

df

t

F

DLL1

5 (1.8)

4.7 (1.6)

4.5 (1.3)

1232

8.8***

32.01***

889

3.26**

10.81***

848

3.00**

9.13***

DLK1

186 (170)

188 (164)

180 (149)

1243

2.23*

10.62***

893

2.00*

11.38***

854

0.08

9.06***

  1. *p < 0.05 **p < 0.03 ***p < 0.001
  2. Abbreviations: M = median; IQR = interquartile range; SCZ = schizophrenia; BD = bipolar disorder; HC = healthy controls; DLL1 = Delta-like protein 1; DLK1 = Delta Like Non-Canonical Notch Ligand 1.
  3. ANCOVA using linear regression models. Results are significant if p < 0.03, and nominally significant if 0.03 < p < 0.05 (Bonferroni correction).
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