Figure 5
From: Vitamin C promotes apoptosis in breast cancer cells by increasing TRAIL expression
Induction of apoptosis in breast cancer cells by vitamin C. (a–c) The effect of vitamin C on cell survival shows the EC50 is at similar levels for healthy breast epithelium and breast cancer cells. (d–f) Apoptotic cells were measured in MDA-MB-231, BT549, and HCC1937 cell lines by colorimetric TUNEL assay after treatment with different doses of vitamin C. Vitamin C at 100 μM, but not 10 μM significantly increases apoptosis. In contrast, GSH (100 μM) has no effect on apoptosis.
