Figure 6
From: Vitamin C promotes apoptosis in breast cancer cells by increasing TRAIL expression
Effect of vitamin C treatment on caspase activation in breast cancer cells. (a) Vitamin C treatment at 100 μM significantly enhances poly caspase activation in MDA-MB-231, BT549 and HCC937 cells. (b–d) Quantification of caspase active cell in MDA-MB-231, BT 549, and HCC1937 cells. (e) Anti-TRAIL antibody blocks caspase activation in MDA-MB-231 cells treated by vitamin C (100 μM). (f) Quantification showing a significant decrease in caspase active cells when anti-TRAIL antibody is applied to vitamin C treated cells.
