Table 2 Group characteristics and biochemical parameters.

From: Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the ‘resistant’ C57Bl/6J mouse strain

 

C

CS

CSU

W

WS

WSU

WU

BW, baseline (g)

22.1 (1.6)

21.7 (0.9)

22.7 (1.1)

21.8 (1.2)

21.5 (1.6)

21.1 (1.1)

22.1 (1.3)

BW, endpoint (g)

30.2 (1.8)

25.2 (2.2)a

21.1 (1.9)b

31.6 (2.3)

27.8 (2.1)e

26.7 (1.7)a,e

32.2 (4.3)

Food intake (g/day)

3.1 (0.17)NT

3.8 (0.5)NT

3.6 (0.4)NT

3.6 (0.3)NT

4.0 (0.4)NT

3.4 (0.4)NT

3.5 (0.5)NT

Caloric intake (kcal/day)

10.8 (0.7)NT

13.2 (1.8)NT

12.6 (1.5)NT

15.8 (1.4)NT

17.9 (2.0)NT

15.1 (1.7)NT

15.9 (2.3)NT

Water intake (g/day)

3.9 (1.3)NT

19.3 (3.5)NT

22.9 (2.3)NT

4.7 (1.5)NT

8.4 (4.5)NT

5.4 (1.3)NT

1.6 (0.9)NT

Urinary volume (ml/day)

1.1 (0.4)

11.0 (12.0)

27.3 (6.0)c

0.5 (0.3)

1.2 (1.3)

3.6 (2.9)a

1.0 (0.7)

Plasma creatinine (uM)

10.3 (3.4)

10.4 (2.0)

11.0 (3.5)

7.9 (2.5)

8.1 (3.4)

10.6 (1.9)

10.5 (2.6)

Plasma Urea (mM)

8.5 (2.4)

7.5 (0.9)g

12.2 (3.1)a

8.0 (1.3)

8.1 (0.6)

9.1 (1.3)

9.0 (0.8)

FBG (mM)

9.7 (1.4)

22.9 (6.3)b

23.5 (3.5)c

9.9 (1.5)

20.5 (4.0)b,e

19.3 (9.9)

10.1 (2.4)

FPI (uU/mL)

26.9 (8.4)

12.8 (2.3)b

11.3 (1.4)c

29.8 (15.7)

12.0 (5.4)a

12.0 (2.7)a,d

21.7 (5.8)

HOMA-IR

11.3 (3.5)

12.8 (3.4)

12.3 (1.2)

12.9 (7.0)

10.6 (3.1)

8.4 (3.1)

9.8 (3.3)

HOMA-beta

87.5 (35)

16.7 (4.9)a

11.3 (3.4)b

84.4 (44)

15.1 (8.6)c,f

20.1 (9.9)b,d

69.6 (28)

Systolic blood pressure (mmHG)

171 (46)

166 (28)

143 (45)

152 (43)

154 (43)

161 (26)

184 (34)

  1. Values are expressed as mean (SD). ap < 0.05,bp < 0.01 and cp < 0.0001 vs its diet control (C or W); dp < 0.05, ep < 0.01 fp < 0.0001 vs WU; gp < 0.01 vs CSU. FBG = fasting blood glucose, FPI = fasting plasma insulin, NTnot tested.
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