Figure 2

Comparison of the bacterial composition among the PSC, UC, and HC groups. (A) The average microbial abundance of the 16 dominant genera with the relative mean abundances of >0.5% are represented. All others are summed into the category “others.” (B) Fold-change of the 16 dominant genera in PSC/HC and UC/HC comparisons, which are calculated by dividing the mean relative abundance (%) of each genus in the PSC and UC groups by that in the HC group, respectively. The mean abundance (%) in the HCs is shown in parentheses. Horizontal axis: The fold-change displayed in log10. Horizontal bars: The fold-change between PSC and HC (red) and between UC and HC (green). *p < 0.05, **p < 0.01, and ***p < 0.001 based on the Kruskal-Wallis test followed by the Steel-Dwass test for multiple comparisons.