Table 3 Intra- and inter-observer agreement for the assessment of quantitative parameters extracted from multimodal retinal imaging in 16 achromatopsia patients.

From: Multimodal imaging including semiquantitative short-wavelength and near-infrared autofluorescence in achromatopsia

 

Intra-observer agreement

Inter-observer agreement between observers 1 & 2

Observer 1

Observer 2

ICC

95% CI

ICC

95% CI

ICC

95% CI

Size of hyper-autofluorescent ring on SW-AF, degree

0.997

0.992–0.999

0.998

0.996–0.999

0.952

0.871–0.983

Size of central hypo-autofluorescence on NIR-AF, degree

0.998

0.994–0.999

0.996

0.990–0.999

0.957

0.885–0.985

Size of ISe alteration on SD-OCT, degree

0.999

0.996–1.0

0.997

0.992–0.999

0.980

0.944–0.993

  1. Agreement was assessed by the intraclass correlation coefficient. The level of agreement was determined by the lower end of the 95% confidence interval, as excellent (>0.90), substantial (0.75–0.90), moderate (0.50–0.75), or poor (<0.50).
  2. ICC = intraclass correlation coefficient.
  3. 95% CI = 95% confidence interval.
  4. SD-OCT = spectral-domain optical coherence tomography.
  5. SW-AF = short-wavelength autofluorescence.
  6. NIR-AF = near-infrared autofluorescences.
  7. ISe = inner segment ellipsoid.
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