Table 4 Potential interaction types of two chemicals. The individual chemical effect is classified directionally: positive direction (+) and negative direction (−).
Interaction Type | Individual effect | Combined effect | Definition |
|---|---|---|---|
AD | ++ | + | Interaction = AD |
−− | − | Interaction = AD | |
+− | 0 | Interaction = AD | |
+A | ++ | + | 0 < Interaction < AD |
++ | − | Interaction < 0 < AD | |
+− | − | Interaction < AD < 0 | |
−A | −− | − | Interaction < AD < 0 |
+− | + | 0 < Interaction < AD | |
+S | ++ | + | 0 < AD < Interaction |
−− | + | AD < 0 < Interaction | |
+− | + | AD < 0 < Interaction; 0 < AD < Interaction | |
−S | −− | − | AD < Interaction < 0 |
+− | − | AD < Interaction < 0 |
