Figure 1
From: Inhibition of homoserine dehydrogenase by formation of a cysteine-NAD covalent complex
The overall structure of StHSD in its ligand-bound, dimeric form. The nucleotide-binding (residues 1–130 and 285–304), dimerization (residues 131–145 and 256–284), and catalytic (residues 146–255) regions of one monomer are shown in red, green, and blue, respectively. The other monomer is shown in gray. The atoms of the cysteine and NADP are shown as purple and cyan spheres, respectively. The disulfide bond between the two Cys304 residues are shown as yellow spheres.
