Table 1 Observational data on cure.

From: Improving treatment outcome assessment in a mouse tuberculosis model

Treatment length

RpZHE

RZME

RZMH

2 months

0/3

0/3a

0/3

2.5 months

1/3

0/3

0/3

3 months

2/3

3/3

0/3

3.5 months

2/3

2/3

0/3

4 months

3/3

2/2b

1/3

4.5 months

2/2c

3/3

2/3

5 months

3/3

3/3

3/3

5.5 months

3/3

2/2b

3/3

6 months

3/3

3/3

3/4d

  1. a0/3 = 0 of 3 mice was cured (culture-negative lungs 3 months post-treatment) after indicated treatment duration; bAnimal died of a non-tuberculosis cause prior to time point; cThe plates for colony counting were contaminated and no counting could be performed; dThe backup mouse included for the RZMH regimen was still alive at the 6 month time point. R = rifampicin, Rp = rifapentine, Z = pyrazinamide, M = moxifloxacin, H = isoniazid, E = Ethambutol.
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