Figure 4
From: Plasmodium falciparum strains spontaneously switch invasion phenotype in suspension culture
Phenotypic switching of Suspended cultures is highly dependent on complement receptor 1 (CR1). Anti-CR1 antibodies (12 µg/mL) inhibited invasion of Suspended (SP) parasites into Nm-treated erythrocytes but not untreated erythrocytes. Invasion rates were determined by flow cytometry as percentage of ring-infected erythrocytes after approximately 14 hours’ incubation and expressed as invasion efficiency relative to invasion into untreated erythrocytes. Data are presented as mean ± standard errors of three independent experiments performed in triplicates. *P-value < 0.05 at 95% CI compared to IgY control; student t-test.
