Figure 2 | Scientific Reports

Figure 2

From: A murine model of atopic dermatitis can be generated by painting the dorsal skin with hapten twice 14 days apart

Figure 2

Change in serum total IgE levels of mice sensitized with DNFB according to Protocol 2, 3, or 4. (a) Six mice underwent weekly DNFB painting sessions (100 µL of 0.15% DNFB) for 3 weeks. They were then painted a fourth time 9 days later (day 23) and divided into three groups of two. Protocols 2, 3, and 4, respectively, involved a fifth painting session 12, 19, or 26 days after the fourth session (on days 35, 42, and 49, respectively). (b) Protocol 2. (c) Protocol 3. (d) Protocol 4. Blood samples were collected from the legs at the indicated time points. The serum IgE concentrations were measured by sandwich ELISA. The x-axis is not drawn to scale. The arrows indicate DNFB painting.

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