Figure 1
From: Anisomycin prevents OGD-induced necroptosis by regulating the E3 ligase CHIP
OGD challenge induces necroptotic cell death. (A–B) Representative western blot, with β-actin used for normalization. RIPK1, RIPK3, p-RIPK3 and p-MLKL in control cells, cells challenged by OGD which were pre-treated with or without Nec-1 (50 μM) were tested. The bars represent the mean ± SEM of five independent experiments. Significant differences *p < 0.05 vs. Control, #p < 0.05 vs. OGD. Related blots are shown in Supplementary Fig. S1.
