Table 1 Subgroups in the patient cohort classified according to the 2016 Update of the WHO Classification of Brain Tumors, and mean kurtosis as well as skewness values of the respective tumor subgroups.
Molecular parameters | Histology | WHO grade | n (median age; M/F) | Median Karnofsky score | Mean diffusional kurtosis ± SD | Skewness diffusional kurtosis ± SD |
|---|---|---|---|---|---|---|
IDH1/2 mutation | Astrocytoma | 2 | 11 (46;7/4) | 90 | 516.19 ± 97.20 | 1.03 ± 0.91 |
Anaplastic astrocytoma | 3 | 4 (49;1/2) | 80 | 482.69 ± 107.76 | 0.82 ± 0.77 | |
Oligodendroglioma | 2 | 6 (52;2/4) | 80 | 504.60 ± 40.65 | 1.66 ± 2.95 | |
Anaplastic oligodendroglioma | 3 | 5 (46;2/3) | 80 | 586.15 ± 64.70 | −0.11 ± 0.74 | |
Pooled | 26 (48;12/13) | 80 | 521.81 ± 85.62 | 0.93 ± 1.61 | ||
IDH1/2 wild type | Astrocytoma | 2 | 2 (50;1/1) | 90 | 648.58 ± 171.56 | 0.88 ± 0.34 |
Anaplastic astrocytoma | 3 | 9 (49;2/1) | 80 | 634.97 ± 137.77 | 2.05 ± 3.17 | |
Pooled | 11(50;3/2) | 80 | 637.45 ± 134.75 | 1.84 ± 2.88 |
