Figure 5 | Scientific Reports

Figure 5

From: Tranilast inhibits the expression of genes related to epithelial-mesenchymal transition and angiogenesis in neurofibromin-deficient cells

Figure 5

Tranilast suppresses the expression of angiogenesis-related genes in sNF96.2 cells. sNF96.2 cells that had been incubated in the absence or presence of tranilast (250 μM) for 48 h were subjected to quantitative RT-PCR analysis of TGF-β1, TGF-β2, IL-8 (CXCL8), VEGF-A, and MMP2 mRNAs. Data are means ± s.d. for triplicates from a representative experiment. *P < 0.05, **P < 0.01, ***P < 0.001 versus corresponding control value (Student’s unpaired t test).

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