Table 3 Selected gene changes in tumor-bearing p204 KO mice.
From: RNA-Seq analysis of interferon inducible p204-mediated network in anti-tumor immunity
#ID | log2FC | WT vs KO | Swissprot_annotation |
|---|---|---|---|
IFI Family members | |||
ENSMUSG00000037849 | −3.87635 | down | Pyrin domain-containing protein 3 GN = Pydc3 |
ENSMUSG00000026536 | −3.45103 | down | Interferon-activable protein 205-B GN = Ifi205b |
ENSMUSG00000034459 | −1.41452 | down | Interferon-induced protein with tetratricopeptide repeats 1 GN = Ifit1 |
ENSMUSG00000026535 | 3.58602 | up | Interferon-activable protein 202 GN = Ifi202 |
Cytokine and its receptors | |||
ENSMUSG00000015966 | 3.046982 | up | Interleukin-17 receptor B (Precursor) GN = Il17rb |
ENSMUSG00000044103 | 1.758106 | up | Interleukin-36 gamma (Precursor) GN = Il36g |
ENSMUSG00000026073 | 1.552664 | up | Interleukin-1 receptor type 2, soluble form (Precursor) GN = Il1r2 |
ENSMUSG00000062157 | 1.334625 | up | Interferon lambda receptor 1 (Precursor) GN = Ifnlr1 |
ENSMUSG00000003206 | 1.149416 | up | Interleukin-27 subunit beta (Precursor) GN = Ebi3 |
ENSMUSG00000026981 | 1.126317 | up | Interleukin-1 receptor antagonist protein (Precursor) GN = Il1rn |
ENSMUSG00000071714 | 1.083263 | up | Interleukin-3 receptor class 2 subunit beta (Precursor) GN = Csf2rb2 |
ENSMUSG00000026070 | 1.009005 | up | Interleukin-18 receptor 1 (Precursor) GN = Il18r1 |
Extracellular matrix | |||
ENSMUSG00000056481 | −1.070622 | down | Endosialin (Precursor) GN = Cd248 |
ENSMUSG00000029304 | 2.492212 | up | Osteopontin (Precursor) GN = Spp1 |
Anti-oxidant activity | |||
ENSMUSG00000021792 | −1.213679 | down | Redox-regulatory protein FAM213A GN = Fam213a |
ENSMUSG00000056054 | 1.446364 | up | Protein S100-A8 GN = S100a8 |
ENSMUSG00000031722 | 1.366310 | up | Haptoglobin beta chain (Precursor) GN = Hp |
ENSMUSG00000056071 | 1.344669 | up | Protein S100-A9 GN = S100a9 |
Chemoattractant | |||
ENSMUSG00000048480 | 2.347394 | up | C-X-C chemokine receptor type 1 GN = Cxcr1 |
ENSMUSG00000026180 | 1.375646 | up | C-X-C chemokine receptor type 2 GN = Cxcr2 |
ENSMUSG00000025804 | 1.330659 | up | C-C chemokine receptor type 1 GN = Ccr1 |
Multi-organism process | |||
ENSMUSG00000006464 | −1.29234 | down | Bardet-Biedl syndrome 1 GN = Bbs1 |
ENSMUSG00000034226 | 1.28859 | up | Rho-related GTP-binding protein RhoV |
Leukocytes adhesion | |||
ENSMUSG00000026580 | 1.632646 | up | P-selectin (Precursor) GN = Selp |
ENSMUSG00000074272 | 1.570366 | up | Carcinoembryonic antigen-related cell adhesion molecule 1 GN = Ceacam1 |
ENSMUSG00000040950 | 1.546964 | up | C-type lectin domain family 10 member A GN = Clec10a |
ENSMUSG00000030786 | 1.402912 | up | Integrin alpha-M (Precursor) GN = Itgam |
ENSMUSG00000034028 | 1.399784 | up | CD226 antigen (Precursor) GN = Cd226 |
ENSMUSG00000029915 | 1.367813 | up | C-type lectin domain family 5 member A GN = Clec5a |
ENSMUSG00000030142 | 1.243278 | up | C-type lectin domain family 4 member E GN = Clec4e |
ENSMUSG00000030342 | 1.193822 | up | CD9 antigen GN = Cd9 |
ENSMUSG00000000157 | 1.169239 | up | Integrin beta-2-like protein (Precursor) |
ENSMUSG00000020689 | 1.163936 | up | Integrin beta-3 (Precursor) GN = Itgb3 |
ENSMUSG00000027111 | 1.157775 | up | Integrin alpha-6 light chain (Precursor) GN = Itga6 |
ENSMUSG00000030144 | 1.137084 | up | C-type lectin domain family 4 member D GN = Clec4d |
ENSMUSG00000053063 | 1.026039 | up | C-type lectin domain family 12 member A GN = Clec12a |
Cell killing activities | |||
ENSMUSG00000014543 | 2.403747 | up | Killer cell lectin-like receptor 5 GN = Klra5 |
ENSMUSG00000015950 | 1.315022 | up | Neutrophil cytosol factor 1 GN = Ncf1 |
ENSMUSG00000057729 | 1.098486 | up | Myeloblastin (Precursor) GN = Prtn3 |
