Figure 6
From: STEAP2 Knockdown Reduces the Invasive Potential of Prostate Cancer Cells

STEAP2 expression is higher in PCa specimens when compared to normal prostate tissue and increases with Gleason score. STEAP2 staining intensity was observed in (A) Normal patient samples and compared to (B) Gleason 6, (C) Gleason 7 (3 + 4), (D) Gleason 7 (4 + 3), (E) Gleason 8 and (F) Gleason 9/10. Staining intensity increased from normal to cancer samples and increased in a stepwise fashion from Gleason 6 to Gleason 9/10. (G) Significant difference in STEAP2 score observed between normal and cancer patients. (H) A significant positive correlation (r = 0.190) between Gleason score and STEAP2 score was determined using a Pearson correlation test. Significance denoted as ***p < 0.001.