Table 1 Definitions and abbreviations of the toxicological endpoints.

From: Time-to-death approach to reveal chronic and cumulative toxicity of a fungicide for honeybees not revealed with the standard ten-day test

Variable

Abbreviation

Definition

Units

Model

Concentration

C

Quantity of test product within the syrup provided as food to the bees

mg a.i./l syrup

 

Dose

D

Quantity of test product actually consumed by the living bees through their food (syrup) on a given day. The calculations were based on syrup consumption, concentration of the test product in the syrup, syrup density (1.23 g/ml) and the number of bees still alive

mg a.i. bee−1 day−1

 

Daily Dietary Dose

DD

Average of the doses consumed during a given day and all preceding days

average mg a.i. bee−1 day−1

 

Cumulative dose

CD

Sum of the doses consumed during a given day and all preceding days

total mg a.i. bee−1

 

Lethal Time

LTx

Number of days of exposure to cause x% mortality at a given concentration

days

Based on the Weibull 2 model: Mortality vs Time

Lethal Concentration

LCx

Concentration needed to cause x% mortality after a given period of exposure

mg a.i./l syrup

Based on the Weibull 2 model: Mortality vs Concentration

Lethal Dietary Dose

LDDx

Average daily dose consumed per bee needed to cause x% mortality after a given period of exposure

average mg a.i. bee−1 day−1

Based on the Weibull 2 model: Mortality vs Daily Dietary Dose

Lethal Cumulative Dose

LCDx

Cumulative doses consumed per bee from day 0 needed to cause x% mortality

total mg a.i. bee−1

Based on the Weibull 2 model: Mortality vs Cumulative Dose