Figure 2

TGF-β1 increased IL-6 mRNA expression, IL-6 production, and α-SMA protein expression in HCFs. (a) IL-6 mRNA expression in the presence of TGF-β1 for 6 hours in HCFs (n = 4, ***p < 0.001). (b) IL-6 production in the presence of TGF-β1 for 24 h (n = 4, ***p < 0.001). (c) TGF-β1-induced increase of α-SMA protein expression after 24 h. (n = 4, ***p < 0.001). The original immunoblot image is shown in Supplemental Fig. 6.