Table 1 Baseline characteristics of study cohort according to different BMI.
Characteristic | BMI < 18.5 | 18.5 ≤ BMI <24 | 24 ≤ BMI <27 | 27 ≤ BMI | P value* |
---|---|---|---|---|---|
n = 130 | n = 1548 | n = 1201 | n = 1143 | ||
Age, mean (SD), y | 59.69 ± 18.55 | 62.92 ± 14.62 | 64.57 ± 13.24 | 60.83 ± 13.29 | <0.0001 |
20–44 | 29 (22.31) | 179 (11.56) | 92 (7.66) | 145 (12.69) | <0.0001 |
45–64 | 39 (30.00) | 617 (39.86) | 473 (39.38) | 517 (45.23) | |
65–74 | 27 (20.77) | 388 (25.06) | 343 (28.56) | 323 (28.26) | |
≥75 | 35 (26.92) | 364 (23.51) | 293 (24.40) | 158 (13.82) | |
Male sex | 50 (38.46) | 843 (54.46) | 753 (62.70) | 645 (56.43) | <0.0001 |
Comorbid conditions before the date index | |||||
DM | 21 (16.15) | 558 (36.05) | 568 (47.29) | 597 (52.23) | <0.0001 |
CAD | 3 (2.31) | 37 (2.39) | 42 (3.50) | 35 (3.06) | 0.3608 |
Stroke | 14 (10.77) | 264 (17.05) | 226 (18.82) | 194 (16.97) | 0.1147 |
Cancer | 24 (18.46) | 151 (9.75) | 110 (9.16) | 94 (8.22) | 0.0021 |
Hypertension | 58 (44.62) | 1109 (71.64) | 982 (81.77) | 985 (86.18) | <0.0001 |
TB | 6 (4.62) | 29 (1.87) | 18 (1.50) | 15 (1.31) | 0.0411 |
COPD | 32 (24.62) | 321 (20.74) | 288 (23.98) | 271 (23.71) | 0.1410 |
Charlson comorbidity index | 0.0006 | ||||
≤3 | 75 (57.69) | 894 (57.75) | 601 (50.04) | 600 (52.49) | |
4–5 | 37 (28.46) | 368 (23.77) | 341 (28.39) | 285 (24.93) | |
>5 | 18 (13.85) | 286 (18.48) | 259 (21.57) | 258 (22.57) | |
Mean (SD) | 3.38 ± 2.50 | 3.53 ± 2.39 | 3.81 ± 2.46 | 3.73 ± 2.41 | 0.0086 |
ACEI used within 1 year before the index date | 18 (13.85) | 245 (15.83) | 204 (16.99) | 195 (17.06) | 0.6507 |
ARB used within 1 year before the index date | 49 (37.69) | 778 (50.26) | 689 (57.37) | 736 (64.39) | <0.0001 |
fibrate used within 1 year before the index date | 0 (0.00) | 94(5.60) | 115 (9.58) | 138(12.07) | <0.0001 |
OHAs used within 1 year before the index date | 17 (13.08) | 443 (28.62) | 484 (40.30) | 543 (47.51) | <0.0001 |
Statin drug used within 1 year before the index date | 20 (15.38) | 430 (27.78) | 380 (31.64) | 423 (37.01) | <0.0001 |
NSAIDs used within 1 year before the index date | 41 (31.54) | 582 (37.60) | 583 (48.54) | 570 (49.87) | <0.0001 |
Initial stage | 0.3179 | ||||
1–3A | 60 (46.15) | 752 (48.58) | 604 (50.29) | 592 (51.79) | |
3B–5 | 70 (53.85) | 796 (51.42) | 597 (49.71) | 551 (48.21) | |
Smoking | 19 (14.62) | 341 (22.03) | 335 (27.89) | 328 (28.70) | <0.0001 |
Alcohol consumption | 8 (6.15) | 140 (9.04) | 119 (9.91) | 150 (13.12) | 0.0018 |
Betel nut chewing | 4 (3.08) | 69 (4.46) | 67 (5.58) | 91 (7.96) | 0.0007 |
AC sugar | 103.88 ± 34.33 | 110.28 ± 37.56 | 118.17 ± 48.87 | 122.35 ± 48.15 | <0.0001 |
Cholesterol | 180.73 ± 41.87 | 182.68 ± 43.48 | 184.04 ± 46.67 | 186.92 ± 47.79 | 0.1281 |
TG | 96.35 ± 57.58 | 119.96 ± 71.46 | 146.93 ± 96.24 | 168.91 ± 125.71 | <0.0001 |
Na | 137.01 ± 14.01 | 139.62 ± 5.16 | 139.26 ± 6.09 | 141.22 ± 46.39 | 0.3487 |
K | 4.82 ± 3.88 | 4.44 ± 0.62 | 4.54 ± 4.48 | 4.67 ± 5.31 | 0.5480 |
Ca | 8.86 ± 0.74 | 8.98 ± 2.63 | 8.97 ± 0.74 | 9.03 ± 0.68 | 0.7959 |
P | 4.17 ± 0.99 | 4.02 ± 1.07 | 3.93 ± 0.96 | 4.04 ± 1.53 | 0.2067 |
UA | 6.71 ± 2.17 | 6.74 ± 2.64 | 7.04 ± 1.88 | 7.25 ± 2.69 | <0.0001 |
Hb | 11.22 ± 3.29 | 11.75 ± 2.53 | 12.31 ± 2.41 | 12.55 ± 2.36 | <0.0001 |
Hct | 32.69 ± 7.35 | 34.77 ± 6.57 | 36.45 ± 6.21 | 37.75 ± 16.11 | <0.0001 |
Albumin | 4.03 ± 0.43 | 4.52 ± 14.58 | 4.09 ± 0.50 | 4.15 ± 1.63 | 0.7929 |
UPCR | 1180.51 ± 6016.47 | 3346.00 ± 90781.26 | 1119.61 ± 3347.45 | 1179.61 ± 2543.57 | 0.6952 |
eGFR | 48.29 ± 38.58 | 50.89 ± 37.03 | 51.14 ± 33.75 | 53.07 ± 35.24 | 0.2775 |