Table 2 Baseline characteristics of CKD stages 1–3a according to different BMI.

From: Relationship between body mass index and renal function deterioration among the Taiwanese chronic kidney disease population

Characteristic

BMI < 18.5

18.5 ≤ BMI <24

24 ≤ BMI <27

27 ≤ BMI

P value*

n = 60

n = 752

n = 604

n = 592

Age, mean (SD), y

56.63 ± 18.63

59.85 ± 15.19

61.87 ± 13.59

58.25 ± 13.78

<0.0001

  20–44

16 (26.67)

124 (16.49)

62 (10.26)

99 (16.72)

<0.0001

  45–64

19 (31.67)

323 (42.95)

281 (46.52)

285 (48.14)

 

  65–74

13 (21.67)

170 (22.61)

152 (25.17)

146 (24.66)

 

  ≥75

12 (20.00)

135 (17.95)

109 (18.05)

62 (10.47)

 

Male sex

23 (38.33)

386 (51.33)

359 (59.44)

338 (57.09)

0.0008

Comorbid conditions before the date index

  DM

10 (16.67)

222 (29.52)

244 (40.40)

263 (44.43)

<0.0001

  Stroke

7 (11.67)

103 (13.70)

89 (14.74)

75 (12.67)

0.7318

  Cancer

10 (16.67)

65 (8.64)

42 (6.95)

40 (6.76)

0.0324

  Hypertension

17 (28.33)

459 (61.04)

438 (72.52)

464 (78.38)

<0.0001

  TB

3 (5.00)

10 (1.33)

7 (1.16)

9 (1.52)

0.1234

  COPD

14 (23.33)

138 (18.35)

128 (21.19)

122 (20.61)

0.5001

Charlson comorbidity index

    

0.3261

  ≤3

41 (68.33)

542 (72.07)

403 (66.72)

402 (67.91)

 

  4–5

15 (25.00)

138 (18.35)

136 (22.52)

123 (20.78)

 

  >5

4 (6.67)

72 (9.57)

65 (10.76)

67 (11.32)

 

  Mean (SD)

2.57 ± 2.31

2.69 ± 2.12

2.92 ± 2.19

2.86 ± 2.12

0.1773

Initial stage

    

0.3175

  1

21 (35.00)

246 (32.71)

170 (28.15)

184 (31.08)

 

  2

22 (36.67)

325 (43.22)

278 (46.03)

278 (46.96)

 

  3a

17 (28.33)

181 (24.07)

156 (25.83)

130 (21.96)

 

ACEI used within 1 year before the index date

4 (6.67)

104 (13.83)

100 (16.56)

99 (16.72)

0.0950

ARB used within 1 year before the index date

16 (26.67)

310 (41.22)

292 (48.34)

331 (55.91)

<0.0001

fibrate used within 1 year before the index date

0 (0.00)

35 (4.65)

53 (8.77)

63 (10.64)

<0.0001

OHAs used within 1 year before the index date

8 (13.33)

172 (22.87)

207 (34.27)

233 (39.36)

<0.0001

Statin drug used within 1 year before the index date

9 (15.00)

193 (25.66)

172 (28.48)

199 (33.61)

0.0012

NSAIDs used within 1 year before the index date

21 (35.00)

264 (35.11)

285 (47.19)

295 (49.83)

<0.0001

Smoking

9 (15.00)

144 (19.15)

150 (24.83)

157 (26.52)

0.0032

Alcohol consumption

7 (11.67)

83 (11.04)

65 (10.76)

90 (15.20)

0.0683

Betel nut chewing

4 (6.67)

26 (3.46)

31 (5.13)

29 (4.90)

0.3408

Fasting sugar

101.10 ± 28.48

109.88 ± 41.03

118.80 ± 49.11

121.97 ± 50.23

<0.0001

Cholesterol

192.11 ± 35.56

187.66 ± 45.76

187.38 ± 47.18

185.50 ± 46.85

0.7213

TG

94.37 ± 69.46

112.97 ± 65.85

142.75 ± 98.22

162.65 ± 137.09

<0.0001

Na

139.11 ± 3.36

139.70 ± 3.42

139.35 ± 9.21

139.58 ± 9.34

0.9546

K

4.17 ± 0.55

4.20 ± 0.46

4.58 ± 7.36

4.63 ± 7.91

0.7857

Ca

9.41 ± 0.85

9.33 ± 5.05

9.09 ± 0.66

9.20 ± 0.67

0.8441

P

3.54 ± 0.65

3.58 ± 0.80

3.43 ± 0.58

3.47 ± 0.59

0.1372

UA

5.89 ± 2.01

5.89 ± 1.54

6.33 ± 1.55

6.67 ± 3.29

<0.0001

Hb

13.23 ± 4.02

13.15 ± 2.42

13.41 ± 1.67

13.75 ± 1.69

<0.0001

Hct

37.38 ± 6.33

38.80 ± 5.43

39.93 ± 4.53

41.86 ± 21.99

0.0008

Albumin

4.04 ± 0.53

4.04 ± 1.17

4.18 ± 0.55

4.40 ± 2.56

0.0883

UPCR

1330.92 ± 8727.33

660.08 ± 2620.22

443.87 ± 1304.68

646.90 ± 2018.90

0.0520

eGFR

82.94 ± 29.17

81.67 ± 28.96

78.57 ± 24.77

81.13 ± 25.26

0.1453

  1. *Categorical variables: chi-squared test; continuous variables: ANOVA.
  2. BMI, body mass index; DM, diabetes mellitus; CAD, coronary artery disease; CKD; chronic kidney disease; OHA, oral hypoglycemic agents; TG, total glycerides; UA, urine albumin; Hb, hemoglobin; Hct, hematocrit; UPCR, urine protein-to-creatinine ratio; eGFR, estimated glomerular filtration rate.