Table 2 Baseline characteristics of CKD stages 1–3a according to different BMI.
Characteristic | BMI < 18.5 | 18.5 ≤ BMI <24 | 24 ≤ BMI <27 | 27 ≤ BMI | P value* |
|---|---|---|---|---|---|
n = 60 | n = 752 | n = 604 | n = 592 | ||
Age, mean (SD), y | 56.63 ± 18.63 | 59.85 ± 15.19 | 61.87 ± 13.59 | 58.25 ± 13.78 | <0.0001 |
20–44 | 16 (26.67) | 124 (16.49) | 62 (10.26) | 99 (16.72) | <0.0001 |
45–64 | 19 (31.67) | 323 (42.95) | 281 (46.52) | 285 (48.14) | |
65–74 | 13 (21.67) | 170 (22.61) | 152 (25.17) | 146 (24.66) | |
≥75 | 12 (20.00) | 135 (17.95) | 109 (18.05) | 62 (10.47) | |
Male sex | 23 (38.33) | 386 (51.33) | 359 (59.44) | 338 (57.09) | 0.0008 |
Comorbid conditions before the date index | |||||
DM | 10 (16.67) | 222 (29.52) | 244 (40.40) | 263 (44.43) | <0.0001 |
Stroke | 7 (11.67) | 103 (13.70) | 89 (14.74) | 75 (12.67) | 0.7318 |
Cancer | 10 (16.67) | 65 (8.64) | 42 (6.95) | 40 (6.76) | 0.0324 |
Hypertension | 17 (28.33) | 459 (61.04) | 438 (72.52) | 464 (78.38) | <0.0001 |
TB | 3 (5.00) | 10 (1.33) | 7 (1.16) | 9 (1.52) | 0.1234 |
COPD | 14 (23.33) | 138 (18.35) | 128 (21.19) | 122 (20.61) | 0.5001 |
Charlson comorbidity index | 0.3261 | ||||
≤3 | 41 (68.33) | 542 (72.07) | 403 (66.72) | 402 (67.91) | |
4–5 | 15 (25.00) | 138 (18.35) | 136 (22.52) | 123 (20.78) | |
>5 | 4 (6.67) | 72 (9.57) | 65 (10.76) | 67 (11.32) | |
Mean (SD) | 2.57 ± 2.31 | 2.69 ± 2.12 | 2.92 ± 2.19 | 2.86 ± 2.12 | 0.1773 |
Initial stage | 0.3175 | ||||
1 | 21 (35.00) | 246 (32.71) | 170 (28.15) | 184 (31.08) | |
2 | 22 (36.67) | 325 (43.22) | 278 (46.03) | 278 (46.96) | |
3a | 17 (28.33) | 181 (24.07) | 156 (25.83) | 130 (21.96) | |
ACEI used within 1 year before the index date | 4 (6.67) | 104 (13.83) | 100 (16.56) | 99 (16.72) | 0.0950 |
ARB used within 1 year before the index date | 16 (26.67) | 310 (41.22) | 292 (48.34) | 331 (55.91) | <0.0001 |
fibrate used within 1 year before the index date | 0 (0.00) | 35 (4.65) | 53 (8.77) | 63 (10.64) | <0.0001 |
OHAs used within 1 year before the index date | 8 (13.33) | 172 (22.87) | 207 (34.27) | 233 (39.36) | <0.0001 |
Statin drug used within 1 year before the index date | 9 (15.00) | 193 (25.66) | 172 (28.48) | 199 (33.61) | 0.0012 |
NSAIDs used within 1 year before the index date | 21 (35.00) | 264 (35.11) | 285 (47.19) | 295 (49.83) | <0.0001 |
Smoking | 9 (15.00) | 144 (19.15) | 150 (24.83) | 157 (26.52) | 0.0032 |
Alcohol consumption | 7 (11.67) | 83 (11.04) | 65 (10.76) | 90 (15.20) | 0.0683 |
Betel nut chewing | 4 (6.67) | 26 (3.46) | 31 (5.13) | 29 (4.90) | 0.3408 |
Fasting sugar | 101.10 ± 28.48 | 109.88 ± 41.03 | 118.80 ± 49.11 | 121.97 ± 50.23 | <0.0001 |
Cholesterol | 192.11 ± 35.56 | 187.66 ± 45.76 | 187.38 ± 47.18 | 185.50 ± 46.85 | 0.7213 |
TG | 94.37 ± 69.46 | 112.97 ± 65.85 | 142.75 ± 98.22 | 162.65 ± 137.09 | <0.0001 |
Na | 139.11 ± 3.36 | 139.70 ± 3.42 | 139.35 ± 9.21 | 139.58 ± 9.34 | 0.9546 |
K | 4.17 ± 0.55 | 4.20 ± 0.46 | 4.58 ± 7.36 | 4.63 ± 7.91 | 0.7857 |
Ca | 9.41 ± 0.85 | 9.33 ± 5.05 | 9.09 ± 0.66 | 9.20 ± 0.67 | 0.8441 |
P | 3.54 ± 0.65 | 3.58 ± 0.80 | 3.43 ± 0.58 | 3.47 ± 0.59 | 0.1372 |
UA | 5.89 ± 2.01 | 5.89 ± 1.54 | 6.33 ± 1.55 | 6.67 ± 3.29 | <0.0001 |
Hb | 13.23 ± 4.02 | 13.15 ± 2.42 | 13.41 ± 1.67 | 13.75 ± 1.69 | <0.0001 |
Hct | 37.38 ± 6.33 | 38.80 ± 5.43 | 39.93 ± 4.53 | 41.86 ± 21.99 | 0.0008 |
Albumin | 4.04 ± 0.53 | 4.04 ± 1.17 | 4.18 ± 0.55 | 4.40 ± 2.56 | 0.0883 |
UPCR | 1330.92 ± 8727.33 | 660.08 ± 2620.22 | 443.87 ± 1304.68 | 646.90 ± 2018.90 | 0.0520 |
eGFR | 82.94 ± 29.17 | 81.67 ± 28.96 | 78.57 ± 24.77 | 81.13 ± 25.26 | 0.1453 |