Table 3 Baseline characteristics of CKD stages 3b-5 according to different BMI.

From: Relationship between body mass index and renal function deterioration among the Taiwanese chronic kidney disease population

Characteristic

BMI < 18.5

18.5 ≤ BMI < 24

24 ≤ BMI <27

27 ≤ BMI

P value*

n = 70

n = 796

n = 597

n = 551

Age, mean (SD), y

62.31 ± 18.21

65.81 ± 13.44

67.3 ± 12.29

63.59 ± 12.17

<0.0001

  20–44

13 (18.57)

55 (6.91)

30 (5.03)

46 (8.35)

<0.0001

  45–64

20 (28.57)

294 (36.93)

192 (32.16)

232 (42.11)

 

  65–74

14 (20.00)

218 (27.39)

191 (31.99)

177 (32.12)

 

  ≥75

23 (32.86)

229 (28.77)

184 (30.82)

96 (17.42)

 

  Male sex

27 (38.57)

457 (57.41)

394 (66.00)

307 (55.72)

<0.0001

Comorbid conditions before the date index

  DM

11 (15.71)

336 (42.21)

324 (54.27)

334 (60.62)

<0.0001

  Stroke

7 (10.00)

161 (20.23)

137 (22.95)

119 (21.60)

0.0765

  Cancer

14 (20.00)

86 (10.80)

68 (11.39)

54 (9.80)

0.0817

  Hypertension

41 (58.57)

650 (81.66)

544 (91.12)

521 (94.56)

<0.0001

  TB

3 (4.29)

19 (2.39)

11 (1.84)

6 (1.09)

0.1720

  COPD

18 (25.71)

183 (22.99)

160 (26.80)

149 (27.04)

0.2785

Charlson comorbidity index

    

0.0001

  ≤3

34 (48.57)

352 (44.22)

198 (33.17)

198 (35.93)

 

  4–5

22 (31.43)

230 (28.89)

205 (34.34)

162 (29.4)

 

  >5

14 (20.00)

214 (26.88)

194 (32.50)

191 (34.66)

 

  Mean (SD)

4.07 ± 2.47

4.32 ± 2.37

4.71 ± 2.39

4.67 ± 2.35

0.0032

Initial stage

    

0.0004

  3b

13 (18.57)

211 (26.51)

199 (33.33)

1748 (31.58)

 

  4

20 (28.57)

290 (36.43)

217 (36.35)

210 (38.11)

 

  5

37 (52.86)

295 (37.06)

181 (30.32)

167 (30.31)

 

ACEI used within 1 year before the index date

14 (20.00)

141 (17.71)

104 (17.42)

96 (17.42)

0.9583

ARB used within 1 year before the index date

33 (47.14)

468 (58.79)

397 (66.50)

405 (73.50)

<0.0001

fibrate used within 1 year before the index date

0 (0.00)

59 (6.81)

62 (10.39)

75 (13.61)

0.0001

OHAs used within 1 year before the index date

9 (12.86)

271 (34.05)

277 (46.40)

310 (56.26)

<0.0001

Statin drug used within 1 year before the index date

11 (15.71)

237 (29.77)

208 (34.84)

224 (40.65)

<0.0001

NSAIDs used within 1 year before the index date

20 (28.57)

318 (39.95)

298 (49.92)

275 (49.91)

<0.0001

Smoking

10 (14.29)

197 (24.75)

185 (30.99)

171 (31.03)

0.0012

Alcohol consumption

1 (1.43)

57 (7.16)

54 (9.05)

60 (10.89)

0.0144

Betel nut chewing

0 (0)

43 (5.40)

36 (6.03)

62 (11.25)

<0.0001

Fasting sugar

106.29 ± 38.81

110.62 ± 34.29

117.57 ± 48.68

122.75 ± 45.95

<0.0001

Cholesterol

170.53 ± 44.69

178.05 ± 40.73

180.6 ± 45.95

188.42 ± 48.77

0.0002

TG

97.98 ± 46.07

126.49 ± 75.81

151.19 ± 94.09

175.51 ± 112.21

<0.0001

Na

136.31 ± 16.04

139.58 ± 5.75

139.21 ± 3.36

142.17 ± 57.76

0.3459

K

5.03 ± 4.46

4.56 ± 0.66

4.52 ± 0.64

4.70 ± 2.73

0.0643

Ca

8.7 ± 0.62

8.86 ± 0.72

8.92 ± 0.76

8.96 ± 0.67

0.0123

P

4.33 ± 1.01

4.16 ± 1.11

4.13 ± 1.00

4.27 ± 1.72

0.2748

UA

7.34 ± 2.1

7.51 ± 3.16

7.74 ± 1.93

7.85 ± 1.68

0.0597

Hb

9.9 ± 1.73

10.64 ± 2.02

11.36 ± 2.55

11.43 ± 2.34

<0.0001

Hct

29.62 ± 6.3

31.77 ± 5.69

33.64 ± 5.97

34.18 ± 6.14

<0.0001

Albumin

4.03 ± 0.39

4.73 ± 17.58

4.04 ± 0.47

4.00 ± 0.49

0.6969

UPCR

1051.59 ± 1584.35

5883.46 ± 126558.14

1803.27 ± 4461.86

1751.97 ± 2901.74

0.7267

eGFR

18.59 ± 10.75

21.81 ± 11.53

23.38 ± 11.79

22.92 ± 11.62

0.0019

  1. *Categorical variables: chi-squared test; continuous variables: ANOVA.
  2. BMI, body mass index; DM, diabetes mellitus; CAD, coronary artery disease; CKD; chronic kidney disease; OHA, oral hypoglycemic agents; TG, total glycerides; UA, urine albumin; Hb, hemoglobin; Hct, hematocrit; UPCR, urine protein-to-creatinine ratio; eGFR, estimated glomerular filtration rate.
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