Table 2 Changes in voiding habits after a single sub-noxious dose of intravesical LPS in URO-OVA/OT-I mice (p-value: One-way ANOVA with LSD post test).

From: Sub-noxious Intravesical Lipopolysaccharide Triggers Bladder Inflammation and Symptom Onset in A Transgenic Autoimmune Cystitis Model: A MAPP Network Animal Study

 

PBS Day 1 (n = 5)

LPS Day 1 (n = 7)

LPS Day 7 (n = 10)

LPS Day 14 (n = 5)

p-value

Average volume voided per micturition, g

0.28 ± 0.033

0.15 ± 0.012

0.17 ± 0.015

0.17 ± 0.019

0.0008

Maximum volume voided per micturition, g

0.56 ± 0.048

0.34 ± 0.054

0.32 ± 0.037

0.29 ± 0.043

0.0044

Total number of voids

5.2 ± 0.583

9.43 ± 0.571

7.3 ± 0.578

7.4 ± 0.748

0.0023

in light

2.0 ± 0.316

3.57 ± 0.571

2.7 ± 0.260

3.0 ± 0.447

0.1087

in dark

3.2 ± 0.490

5.86 ± 0.404

4.4 ± 0.541

4.4 ± 1.030

0.0645

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