Table 3 Acid-base balance, electrolytes, respiratory analyses, blood counts, and coagulation parameters evaluated immediately before initiating anesthesia and intraoperative transfusions in ABO-C and ABO-I liver transplant recipients after propensity score matching analysis.

From: Prevalent metabolic derangement and severe thrombocytopenia in ABO-incompatible liver recipients with pre-transplant plasma exchange

 

ABO-C (n = 199)

ABO-I (n = 199)

P value

Acid-base balance

pH

7.45 ± 0.03

7.47 ± 0.04

<0.001

pH ≥ 7.50, %

11 (5.5)

47 (23.6)

<0.001

Base excess, mmEq/l

1.39 ± 2.39

4.97 ± 3.76

<0.001

HCO3−, mmEq/l

25.5 ± 2.8

29.1 ± 3.8

<0.001

HCO3− > 30 mmEq/l, %

7 (3.5)

56 (28.1)

<0.001

PaCO2, mmHg

37 ± 4.96

39 ± 4.95

<0.001

PaCO2 > 45 mmHg, %

6 (3.0)

18 (9.0)

0.021

PaO2, mmHg

88.0 ± 10.6

84.3 ± 11.2

0.001

PaO2 ≤ 80 mmHg

49 (24.6)

80 (40.2)

0.001

Lactic acid, mmol/l

0.99 ± 0.37

1.07 ± 0.36

0.004

Electrolyte analysis

Sodium, mmol/l

136 ± 4.13

138 ± 3.4

0.001

Potassium, mmol/l

3.7 ± 0.43

3.4 ± 0.45

<0.001

Potassium ≤ 3 mmol/l, %

13 (6.5)

35 (17.6)

0.001

Magnesium, mg/dl

1.98 ± 0.25

1.86 ± 0.23

<0.001

Magnesium ≤ 1.7 mg/dl, %

20 (10.1)

55 (27.6)

<0.001

Total calcium, mmol/l

2.03 ± 0.15

2.07 ± 0.18

0.011

Ionised calcium, mmol/l

1.11 ± 0.07

1.12 ± 0.07

0.443

Ratio of total to ionised calcium >2.1, %

7 (3.5)

18 (9.0)

0.039

Coagulation parameters

Platelets, ×103 /µl

64 (49–91)

47 (32–72)

<0.001

Platelets <30 × 103 /µl

12 (6.0)

38 (19.1)

<0.001

Fibrinogen, mg/dl

173 (131–226)

165 (145–193)

0.256

Antithrombin III,%

52 (34–70)

61 (50–75)

<0.001

PT, INR

1.33 (1.14–1.55)

1.25 (1.14–1.42)

0.018

aPTT, s

33 (29–37)

31 (28–34)

<0.001

Transfusion

Packed red blood cell transfusion, units

6.0 (2.0–14.0)

7.0 (3.0–12.0)

0.910

Fresh frozen plasma transfusion, units

8.0 (3.0–14.5)

7.0 (2.0–12.0)

0.165

Cryoprecipitate transfusion, units

10.0 (0–10)

10.0 (0–10)

0.207

Apheresis platelet transfusion, %

102 (51.3)

126 (63.3)

0.020

  1. *Values are expressed as mean (±standard deviation) or median and interquartile range as appropriate, and n (%) for categorical variables. ABO-C, ABO-compatible; ABO-I, ABO-incompatible; aPTT, activated partial thromboplastin time; INR, international normalised ratio; PT, prothrombin time.
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