Figure 6 | Scientific Reports

Figure 6

From: JIB-04, A Small Molecule Histone Demethylase Inhibitor, Selectively Targets Colorectal Cancer Stem Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway

Figure 6

Transcriptome analysis of HCT116 cells after treatment with JIB-04. (A) KEGG pathway enrichment analysis. Raw p-values were calculated by modified Fisher’s exact test. The pathway enrichment scores (−Log10 P-value) among the differentially expressed genes are shown. (B) Scatter plot of differential gene expression between 2 µM JIB-04 treatment and DMSO treatment. (C) Differential expression of genes related to the Wnt/β-catenin signaling pathway between 2 µM JIB-04 treatment and DMSO treatment.

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