Figure 4
The most parsimonious hypothesis that explains the distribution of genes into classes summarized in Table 1. Whole genome duplications30,64 are indicated as blue ellipses, black rectangles indicate gene losses and red arrows are gene emergences or duplications. The emergences of the HUL4A and HUL5 genes, after the Fonticula/fungi split, are indicated in brackets because animal data indicate an earlier origin for these genes that it is shown here (see main text). The topology of the tree was obtained from refs29,35,65,66,67,68.
