Figure 5

Maximum Likelihood phylogenetic tree of fungal and animal HECT sequences. The best ML value was obtained with the LG + R10 model of sequence evolution and perturbation strength = 0.5. Numbers indicate ultrafast bootstrap support. Blue: fungal groups. In all cases but HUL4A, they correspond to the fungal HECT subfamilies shown in Fig. 2. HUL4A subfamily sequences are here divided into two groups. Red: animal subfamilies; these groups include a sequence of the choanoflagellate Monosiga brevicollis. Black: animal subfamilies for which no orthologous choanoflagellate sequences were found.