Figure 3 | Scientific Reports

Figure 3

From: Thymidine catabolism promotes NADPH oxidase-derived reactive oxygen species (ROS) signalling in KB and yumoto cells

Figure 3

Levels of PPP intermediates in KB/TP cells after addition of thymidine. (a) KB/TP were incubated in serum-free medium with 500 μM thymidine for the indicated times, and levels of metabolites were determined using CE-TOFMS. (b) KB cells transfected with DERA siRNA were treated with 500 μM thymidine for 48 h and the intracellular levels of NADPH were determined. (c) Effect of DERA and G6PD downregulation on IL-8 mRNA levels in KB/TP cells. Data are presented as mean ± SD. ∗P < 0.01.

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