Figure 4
From: A proteomic analysis of an in vitro knock-out of miR-200c
Bioinformatic analysis of the proteomic dataset. (a) Targets for DAVID 6.7 analysis with the GOterm BP database were chosen from the whole dataset for every protein with p ≤ 0.05 after student’s t-test KO vs Ctrl (b) Distribution of ES Scores in a GSEA of KO vs Ctrl with Gene Ontology (c5.all.v5.2) and KEGG (c2.cp.kegg.v5.2) reference database (c) GSEA Enrichment-Plot analysis of the whole dataset shows two exemplary KEGG pathways. Oxidative phosphorylation and focal adhesion showing overexpression while (d) cell cycle and regulation of actin cytoskeleton are being down regulated.
