Table 1 Targets with significant difference between both groups – M1 and M2 and M3 vs MCF7 and MCtrl.
From: A proteomic analysis of an in vitro knock-out of miR-200c
Protein | Gene | p-Value | fold change | Expression | Function |
|---|---|---|---|---|---|
Anterior gradient protein 2 homolog | AGR2 | 6.36 × 10−3 | 0.59 | down | Migration |
Filamin-A | FLNA | 4.32 × 10−5 | 1.31 | up | Migration |
Filamin-B | FLNB | 1.20 × 10−5 | 1.41 | up | Migration |
Glutathione S-transferase Mu 3 | GSTM3 | 1.43 × 10−5 | 3.54 | up | De-Tox |
Pyridoxal kinase | PDXK | 2.27 × 10−3 | 0.53 | down | Metabolism |
4F2 cell-surface antigen heavy chain | SLC3A2 | 1.25 × 10−4 | 2.00 | up | Apoptosis |
Spectrin alpha chain, non-erythrocytic 1 | SPTAN1 | 3.26 × 10−4 | 0.73 | down | Migration |
Tropomyosin alpha-1 chain | TPM1 | 3.74 × 10−3 | 1.93 | up | Migration |
UDP-glucose 6-dehydrogenase | UGDH | 7.10 × 10−3 | 0.39 | down | Migration |
