Table 1 Association between microarray results and Real-time RT-PCR results for 22 candidates of up-regulated miRNAs.
From: Identification of miRNAs in cervical mucus as a novel diagnostic marker for cervical neoplasia
miRNAs | Microarray | Microarray | Realtime RT-PCR | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
group category | global normalization (absolute value) | Fold-change(disease/normal) | Fold-change(disease/normal) | ||||||||||||
Normal | CIN1 | CIN3 | SCC | AD | Normal | CIN1 | CIN3 | SCC | AD | Normal | CIN1 | CIN3 | SCC | AD | |
hsa-miR-144-3p | 14.0 | 26.5 | 48.6 | 577.5 | 2249.5 | 1.0 | 1.9 | 3.5 | 41.3 | 160.9 | 1.0 | 0.5 | 3.2 | 219.4 | 74.1 |
hsa-miR-451a | 567.7 | 1170.8 | 1931.7 | 29968.6 | 52690.1 | 1.0 | 2.1 | 3.4 | 52.8 | 92.8 | 1.0 | 0.9 | 5.1 | 369.3 | 65.6 |
hsa-miR-141-3p | 44.0 | 123.2 | 140.0 | 275.0 | 515.5 | 1.0 | 2.8 | 3.2 | 6.2 | 11.7 | 1.0 | 1.1 | 1.1 | 2.3 | 1.4 |
hsa-miR-10a-5p | 5.0 | 14.7 | 32.3 | 33.4 | 219.0 | 1.0 | 2.9 | 6.4 | 6.6 | 43.5 | 1.0 | 1.1 | 1.1 | 1.3 | 2.2 |
hsa-miR-126-3p | 7.5 | 7.7 | 11.6 | 118.4 | 302.9 | 1.0 | 1.0 | 1.5 | 15.7 | 40.1 | 1.0 | 1.2 | 1.2 | 23.4 | 9.7 |
hsa-miR-20b-5p | 129.0 | 93.9 | 91.9 | 512.9 | 1168.0 | 1.0 | 0.7 | 0.7 | 4.0 | 9.1 | 1.0 | 0.8 | 0.7 | 8.3 | 4.3 |
hsa-miR-205-5p | 318.6 | 813.3 | 947.8 | 2818.2 | 1189.2 | 1.0 | 2.6 | 3.0 | 8.8 | 3.7 | 1.0 | 1.6 | 1.3 | 2.5 | 1.3 |
hsa-let-7f-5p | 196.3 | 207.8 | 215.3 | 832.3 | 1853.0 | 1.0 | 1.1 | 1.1 | 4.2 | 9.4 | 1.0 | 0.6 | 0.5 | 1.7 | 1.0 |
hsa-miR-106a-5p | 230.2 | 157.6 | 154.7 | 1050.4 | 2105.3 | 1.0 | 0.7 | 0.7 | 4.6 | 9.1 | 1.0 | 0.6 | 0.5 | 2.3 | 1.8 |
hsa-miR-17-5p | 218.7 | 142.5 | 156.2 | 963.7 | 1960.3 | 1.0 | 0.7 | 0.7 | 4.4 | 9.0 | 1.0 | 0.6 | 0.5 | 2.3 | 1.7 |
hsa-let-7a-5p | 340.0 | 438.0 | 504.8 | 1246.3 | 2766.3 | 1.0 | 1.3 | 1.5 | 3.7 | 8.1 | 1.0 | 0.8 | 0.6 | 1.8 | 1.3 |
hsa-let-7b-5p | 259.2 | 403.4 | 432.4 | 1078.2 | 1874.1 | 1.0 | 1.6 | 1.7 | 4.2 | 7.2 | 1.0 | 1.2 | 0.8 | 1.8 | 2.1 |
hsa-let-7c-5p | 252.4 | 375.5 | 393.6 | 1020.7 | 1805.7 | 1.0 | 1.5 | 1.6 | 4.0 | 7.2 | 1.0 | 0.8 | 0.5 | 0.6 | 0.8 |
hsa-miR-16-5p | 1431.1 | 883.2 | 933.7 | 5119.7 | 10212.9 | 1.0 | 0.6 | 0.7 | 3.6 | 7.1 | 1.0 | 0.7 | 0.8 | 2.4 | 1.8 |
hsa-let-7d-5p | 274.0 | 340.0 | 343.7 | 1029.9 | 1806.1 | 1.0 | 1.2 | 1.3 | 3.8 | 6.6 | 1.0 | 0.7 | 0.6 | 1.6 | 1.4 |
hsa-miR-21-5p | 556.3 | 1209.4 | 1360.6 | 4170.5 | 3360.7 | 1.0 | 2.2 | 2.4 | 7.5 | 6.0 | 1.0 | 1.1 | 1.7 | 3.9 | 1.8 |
hsa-miR-19b-3p | 296.4 | 180.5 | 192.6 | 877.0 | 1701.3 | 1.0 | 0.6 | 0.6 | 3.0 | 5.7 | 1.0 | 0.6 | 0.6 | 2.1 | 1.5 |
hsa-miR-20a-5p | 193.4 | 130.1 | 137.4 | 812.6 | 1746.0 | 1.0 | 1.9 | 1.8 | 6.7 | 18.8 | 1.0 | 0.7 | 0.6 | 2.3 | 1.4 |
hsa-miR-15b-5p | 186.5 | 121.0 | 124.0 | 562.6 | 1073.8 | 1.0 | 0.6 | 0.7 | 3.0 | 5.8 | 1.0 | 1.2 | 1.3 | 3.5 | 4.4 |
hsa-miR-224-5p | 15.2 | 35.3 | 40.4 | 90.9 | 53.9 | 1.0 | 2.3 | 2.7 | 6.0 | 3.6 | 1.0 | 1.1 | 1.4 | 3.2 | 1.5 |
hsa-miR-155-5p | 5.4 | 11.2 | 10.4 | 52.8 | 28.6 | 1.0 | 2.1 | 1.9 | 9.7 | 5.3 | 1.0 | 2.3 | 2.1 | 8.1 | 2.1 |
hsa-miR-182-5p | 7.8 | 14.8 | 14.1 | 52.2 | 146.0 | 1.0 | 1.9 | 1.8 | 6.7 | 18.8 | 1.0 | 0.8 | 0.7 | 2.8 | 2.6 |
