Figure 1
From: Chronic features of allergic asthma are enhanced in the absence of resistin-like molecule-beta
Schematic representation of the timeline in the severe asthma with fungal sensitization model (SAFS). Age and gender-matched mice are administered antigen from Aspergillus fumigatus extract via subcutaneous (SQ) and intraperitoneal (IP) injections. Following a 2 week rest period, antigen is administered via intranasal (IN) route once a week for three weeks. Sensitized mice are then exposed to conidia liberated from live fungal cultures for 10 minutes at a time two weeks apart via inhalation (IH). Samples were harvested at days 7 and 35 after the second fungal challenge.
