Figure 1
From: Specific features of human monocytes activation by monophosphoryl lipid A
TNF and IL-1β production by human blood adherent mononuclear cells stimulated with 100 ng/ml conventional Escherichia coli smooth LPS O111:B4 (cLPS), highly purified smooth Salmonella abortus equi LPS (hpLPS), highly purified rough S. minnesota Re595 LPS (LPS Re) or 1 µg/ml MPLA. (A) Individual responsiveness of n = 34 individuals. (B) Correlations between individual responsiveness to cLPS and hpLPS in terms of TNF and IL-1β production. (C) Correlations between individual responsiveness to MPLA and hpLPS in terms of TNF and IL-1β production. (D) Correlations between individual responsiveness to rough Re LPS and cLPS or MPLA and in terms of TNF. Each dot represents one individual donor. ****p < 0.0001.
