Table 2 The correlations between cytoplasmic HuR expression and the clinical features of GC patients. P value < 0.05 was indicated in bold.
Variable | N | Cytoplasmic HuR expression | p value | |||
|---|---|---|---|---|---|---|
negative | % | positive | % | |||
Sex | 251 | |||||
Male | 178 | 122 | 68.5 | 56 | 31.5 | 0.668 |
Female | 73 | 48 | 65.8 | 25 | 34.2 | |
Age | ||||||
<60 | 80 | 60 | 75 | 20 | 25 | 0.092 |
≥60 | 171 | 110 | 64.3 | 61 | 35.7 | |
Depth of invasion | ||||||
T1-T3 | 82 | 65 | 79.3 | 17 | 20.7 | 0.006 |
T4 | 169 | 105 | 62.1 | 64 | 37.9 | |
Lymph node metastasis | ||||||
Absent (N0) | 104 | 79 | 76.0 | 25 | 24.0 | 0.019 |
Present (N1- N3) | 147 | 91 | 61.9 | 56 | 38.1 | |
Distant metastasis | ||||||
M0 | 226 | 163 | 72.1 | 63 | 27.9 | <0.001 |
M1 | 25 | 7 | 28.0 | 18 | 72.0 | |
TNM Stage | ||||||
1 + 2 | 116 | 92 | 79.3 | 24 | 20.7 | <0.001 |
3 + 4 | 135 | 78 | 57.8 | 57 | 42.2 | |
Tumor size (cm) | ||||||
>5 | 93 | 61 | 65.6 | 32 | 34.4 | 0.578 |
≤5 | 158 | 109 | 69.0 | 49 | 31.0 | |
Differentiation status | ||||||
Well/Moderate | 147 | 101 | 68.7 | 46 | 31.3 | 0.693 |
Poor/Undifferentiated | 104 | 69 | 66.3 | 35 | 33.7 | |
TTP-expression | ||||||
TTP-high | 101 | 69 | 68.3 | 32 | 31.7 | 0.870 |
TTP-low | 150 | 101 | 67.3 | 49 | 32.7 | |
