Table 4 Univariate and multivariate analyses for the overall survival of GC patients. P value < 0.05 was indicated in bold.

From: Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1

Variable

p-value

Hazard ration (95.0% CI)

Univariate analysis

 Age

0.013

1.856 (1.137–3.030)

 Sex

0.986

0.996 (0.631–1.573)

 Depth of invasion (T)

<0.001

1.970 (1.416–2.740)

 Lymph node metastasis (N)

<0.001

1.926 (1.609–2.305)

 Distant metastasis (M)

<0.001

7.881 (4.717–13.168)

 TNM stage (3, 4 vs 1, 2)

<0.001

3.306 (2.437–4.485)

 TTP expression

0.018

0.585 (0.375–0.910)

 Nuclear HuR expression

0.003

2.137 (1.298–3.517)

 Tumor size

<0.001

2.832 (1.859–4.316)

 Differentiation status

0.042

0.649 (0.428–0.984)

 Cytoplasmic HuR expression

<0.001

3.172 (2.136–4.710)

Multivariate analysis

 Cytoplasmic HuR expression

0.020

1.699 (1.088–2.654)

 Nuclear HuR expression

0.031

1.748 (1.054–2.900)

 Distant metastasis

0.001

3.432 (1.971–5.977)

 TNM stage (3, 4 vs 1, 2)

0.010

3.057 (1.050–6.471)

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