Figure 4
Knockdown of lincDUSP results in gene expression changes in cell cycle control pathways. (A) Verification of lincDUSP knock down by qRT-PCR prior to utilizing the RNA for RNA-seq. (B) Volcano plot of gene expression changes upon lincDUSP KD in V703 cells assayed by RNA-Seq. Genes with significantly decreased expression are shown in blue; genes with significantly increased expression are shown in red; LINC01605 (lincDUSP) shown in yellow. (C) Summary of significantly enriched pathways in V703 cells post lincDUSP KD (FDR < 0.05). The complete data is presented in Supporting Data File 3.
