Table 1 Haemodynamics of the study groups during the 24-hour interventional period.

From: Comparison of first-line and second-line terlipressin versus sole norepinephrine in fulminant ovine septic shock

Variable

Group

Shock time

4 h

8 h

16 h

24 h

CVP [mmHg]

Control

1 [0; 4]

7 [4; 8]

5 [2; 13]

11 [9; 17]

17 [12; 18]

TP first-line

1 [0; 2]

4 [1; 9]

7 [2; 11]

5 [3; 9]

12 [7; 13]

TP second-line

0 [0; 0]

2 [1; 4]

4 [2; 7]

8 [4; 10]

12 [6; 14]

EVLWI [mL·kg-1]

Control

13 [12; 17]

14 [11; 15]

14 [10; 15]

12 [11; 12]

12 [11; 17]

TP first-line

14 [12; 21]

14 [12; 15]

15 [13; 18]

13 [12; 15]

12 [11; 13]

TP second-line

13 [12; 16]

13 [12; 16]

14 [13; 19]

14 [11; 19]

11 [11; 13]

GEDI [mL·m−2]

Control

606 [494; 644]

760 [728; 848]

741 [642; 781]

631 [572; 695]

641 [616; 766]

TP first-line

599 [528; 739]

791 [665; 847]

740 [668; 833]

691 [665; 788]

700 [603; 730]

TP second-line

509 [409; 595]

725 [663; 801]

708 [683; 810]

686 [596; 720]

656 [598; 788]

MAP [mmHg]

Control

40 [36; 54]

60 [56; 61]

60 [58; 61]

63 [60; 64]

62 [61; 63]

TP first-line

46 [35; 49]

60 [50; 62]

61 [59; 63]

64 [63; 64]

61 [60; 61]

TP second-line

39 [34; 41]

58 [58; 61]

60 [56; 61]

63 [61; 65]

60 [54; 60]

SVI [mL·m−2]

Control

28 [24; 35]

57 [48; 70]

57 [44; 74]

48 [45; 66]

59 [47; 74]

TP first-line

24 [19; 30]

39 [36; 52]

57 [41; 66]

45 [44; 50]

50 [38; 57]

TP second-line

23 [21; 29]

50 [45; 58]

56 [48; 62]

33 [23; 56]

33 [23; 56]

SVRI [dyn·s/cm−5·m−2]

Control

1497 [1208; 1883]

630 [449; 1037]

612 [515; 1001]

727 [548; 926]

846 [458; 886]

TP first-line

1352 [1276; 1912]

729 [513; 946]

680 [518; 1000]

993 [799; 1223]

741 [609; 1028]

TP second-line

1509 [1434; 1647]

666 [617; 857]

603 [531; 718]

818 [638; 1037]

741 [559; 1405]

SVV [%]

Control

11 [8; 13]

12 [11; 15]

11 [9; 16]

12 [9; 16]

14 [10; 18]

TP first-line

8 [5; 11]

10 [9; 16]

13 [12; 14]

12 [10; 12]

14 [12; 15]

TP second-line

16 [11; 19]

12 [11; 14]

15 [11; 17]

11 [10; 14]

14 [10; 19]

  1. Values are presented as median [interquartile range].
  2. CVP, central venous pressure; EVLWI, extravascular lung water index; GEDI, global end-diastolic index; SVI, stroke volume index; SVRI, systemic vascular resistance index; SVV, stroke volume variation; TP, Terlipressin.