Table 1 Haemodynamics of the study groups during the 24-hour interventional period.
Variable | Group | Shock time | 4 h | 8 h | 16 h | 24 h |
---|---|---|---|---|---|---|
CVP [mmHg] | Control | 1 [0; 4] | 7 [4; 8] | 5 [2; 13] | 11 [9; 17] | 17 [12; 18] |
TP first-line | 1 [0; 2] | 4 [1; 9] | 7 [2; 11] | 5 [3; 9] | 12 [7; 13] | |
TP second-line | 0 [0; 0] | 2 [1; 4] | 4 [2; 7] | 8 [4; 10] | 12 [6; 14] | |
EVLWI [mL·kg-1] | Control | 13 [12; 17] | 14 [11; 15] | 14 [10; 15] | 12 [11; 12] | 12 [11; 17] |
TP first-line | 14 [12; 21] | 14 [12; 15] | 15 [13; 18] | 13 [12; 15] | 12 [11; 13] | |
TP second-line | 13 [12; 16] | 13 [12; 16] | 14 [13; 19] | 14 [11; 19] | 11 [11; 13] | |
GEDI [mL·m−2] | Control | 606 [494; 644] | 760 [728; 848] | 741 [642; 781] | 631 [572; 695] | 641 [616; 766] |
TP first-line | 599 [528; 739] | 791 [665; 847] | 740 [668; 833] | 691 [665; 788] | 700 [603; 730] | |
TP second-line | 509 [409; 595] | 725 [663; 801] | 708 [683; 810] | 686 [596; 720] | 656 [598; 788] | |
MAP [mmHg] | Control | 40 [36; 54] | 60 [56; 61] | 60 [58; 61] | 63 [60; 64] | 62 [61; 63] |
TP first-line | 46 [35; 49] | 60 [50; 62] | 61 [59; 63] | 64 [63; 64] | 61 [60; 61] | |
TP second-line | 39 [34; 41] | 58 [58; 61] | 60 [56; 61] | 63 [61; 65] | 60 [54; 60] | |
SVI [mL·m−2] | Control | 28 [24; 35] | 57 [48; 70] | 57 [44; 74] | 48 [45; 66] | 59 [47; 74] |
TP first-line | 24 [19; 30] | 39 [36; 52] | 57 [41; 66] | 45 [44; 50] | 50 [38; 57] | |
TP second-line | 23 [21; 29] | 50 [45; 58] | 56 [48; 62] | 33 [23; 56] | 33 [23; 56] | |
SVRI [dyn·s/cm−5·m−2] | Control | 1497 [1208; 1883] | 630 [449; 1037] | 612 [515; 1001] | 727 [548; 926] | 846 [458; 886] |
TP first-line | 1352 [1276; 1912] | 729 [513; 946] | 680 [518; 1000] | 993 [799; 1223] | 741 [609; 1028] | |
TP second-line | 1509 [1434; 1647] | 666 [617; 857] | 603 [531; 718] | 818 [638; 1037] | 741 [559; 1405] | |
SVV [%] | Control | 11 [8; 13] | 12 [11; 15] | 11 [9; 16] | 12 [9; 16] | 14 [10; 18] |
TP first-line | 8 [5; 11] | 10 [9; 16] | 13 [12; 14] | 12 [10; 12] | 14 [12; 15] | |
TP second-line | 16 [11; 19] | 12 [11; 14] | 15 [11; 17] | 11 [10; 14] | 14 [10; 19] |