Table 2 Metabolism, oxygenation and temperature of the study groups during the 24-hour interventional period.
Variable | Group | Shock time | 4 h | 8 h | 16 h | 24 h |
|---|---|---|---|---|---|---|
pH(a) [-lg c(H+)] | Control | 7.44 [7.38; 7.48] | 7.45 [7.43; 7.48] | 7.42 [7.40; 7.45] | 7.38 [7.16; 7.40] | 7.22 [6.99; 7.27] |
TP first-line | 7.39 [7.37; 7.44] | 7.41 [7.35; 7.46] | 7.42 [7.34; 7.45] | 7.31 [7.23; 7.31] | 7.20 [7.20; 7.24] | |
TP second-line | 7.45 [7.40; 7.49] | 7.43 [7.40; 7.45] | 7.39 [7.33; 7.44] | 7.28 [7.10; 7.41] | 7.10 [6.80; 7.31] | |
BE [mmol·L−1] | Control | 7.0 [3.5; 8.5] | 3.0 [2.2; 4.5] | 2.2 [−0.3; 3.7] | −2,4 [−5.4; 1.7] | −5.6 [−7.2; −3.4] |
TP first-line | 4.9 [2.1; 5.4] | 1.0 [0.4; 1.9] | 0.8 [−2.3; 1.9] | −3.3 [−3.6; −2.6] | −5.5 [−6.7; −5] | |
TP second-line | 6.6 [3.5; 7.4] | 2.3 [1.4; 2.8] | 1.4 [0.7; 3.2] | −3.2 [−7.1; 0.8] | −6.1 [−6.5; −4.9] | |
DO2I [mL·min−1·m−2] | Control | 314 [251; 353] | 608 [484; 727] | 600 [456; 675] | 467 [339; 642] | 486 [348; 624] |
TP first-line | 415 [387; 657] | 585 [507; 605] | 543 [376; 661] | 473 [331; 588] | 559 [369; 674] | |
TP second-line | 243 [210; 357] | 563 [418; 642] | 669 [497; 793] | 565 [488; 695] | 466 [399; 481] | |
VO2I [mL·min−1·m−2] | Control | 118 [98; 130] | 79 [74; 91] | 80 [65; 107] | 74 [52; 101] | 66 [47; 79] |
TP first-line | 167 [107; 221] | 120 [93; 130] | 86 [55; 116] | 63 [43; 66] | 58 [43; 73] | |
TP second-line | 123 [90; 138] | 97 [70; 105] | 76 [64; 107] | 72 [59; 92] | 48 [44; 62] | |
O2-ER [mL·min−1·m−2] | Control | 40 [39; 45] | 14 [12; 19] | 15 [11; 22] | 19 [13; 21] | 17 [11; 19] |
TP first-line | 37 [31; 42] | 19 [14; 27] | 14 [11; 20] | 13 [10; 17] | 11 [7; 17] | |
TP second-line | 48 [36; 52] | 20 [14; 24] | 14 [11; 16] | 13 [12; 15] | 16 [10; 18] | |
ScvO2 [%] | Control | 61 [60; 65] | 85 [82; 87] | 84 [80; 87] | 81 [80; 84] | 80 [79; 86] |
TP first-line | 69 [64; 73] | 84 [77; 88] | 85 [78; 90] | 87 [81; 90] | 85 [78; 90] | |
TP second-line | 53 [47; 64] | 83 [78; 86] | 88 [83; 90] | 82 [78; 87] | 69 [60; 84] | |
Temperature [°C] | Control | 39.4 [39.2; 40.1] | 39.3 [38.7; 39.9] | 39.4 [39.1; 40.0] | 39.2 [38.7; 39.4] | 39.5 [38.5; 39.6] |
TP first-line | 40.0 [39.8; 40.5] | 39.6 [38.9; 40.6] | 39.7 [38.4; 40.9] | 39.7 [38.7; 41.2] | 39.6 [39.0; 41.1] | |
TP second-line | 40.3 [39.9; 40.4] | 39.2 [39.1; 39.6] | 39.6 [39.3; 40.0] | 39.9 [39.4; 40.1] | 39.7 [39.2; 40.9] |
