Figure 5

Schematic representation of the infusion line used in the pediatric department. The carrier fluid (i.e. 5% dextrose with electrolytes) was infused through a first 4-stopcock set dedicated to discontinuous drug infusions (acyclovir, acetaminophen and omeprazole). The infusion set was connected to a 150-cm extension line, connected to a second 4-stopcock set for continuous drug infusions (i.e. piperacillin/tazobactam, vancomycin and cyclosporin). A 350-cm extension line was then added to the infusion line (V = 11.00 mL). The infusion line was finally connected to the Qicpic instrument, with or without the central venous catheter (CVC). For all experiments, the infusion flow rate of the carrier fluid was 40 mL.h⁻¹.