Figure 4

Heatmap of proteins differentially abundant in EV in response to treatment of H. capsulatum with 6B7 and 7B6 mAb against Hsp60. The heatmap was generated using Multiexperiment Viewer and clustered by hierarchical clustering based on the abundance profiles. The significantly enriched functions (p ≤ 0.05 by Fisher’s exact test, 2 folds enrichment compared to the genome background) are listed for each cluster. The gray spot represents hits below the limit of quantification.