Figure 2
From: Dramatic dysbalancing of the Wnt pathway in breast cancers
Distribution of the correlation coefficiets for the Wnt genes overlayed on average distribution of correlation coefficients in 500 random genes set in healthy tissues (a); TNBC (b) or non-TNBC (c) tumors. Pathway-related genes show significantly higher numbers of positive strong correlations as compared to the random genes in the healthy breast tissue, while gene co-regulation is dramatically lost in cancer both for random genes and Wnt pathway gene sets. The pathway distributions are narrower and more right-shifted as compared to average random set. P values are given from Kolmogorov-Smirnov test indicating unequality of distributions.
