Figure 3
From: Dramatic dysbalancing of the Wnt pathway in breast cancers
Comparison of the Wnt pathway components expression level correlations in healthy breast and breast cancer. Panel (a) shows clustering using the complete linkage algorithm for pairwise correlations in healthy breast (lower triangle of the heatmap) and for those observed in non-TNBC samples (upper triangle). The correlation clusters are highlighted by lines and numbered; the cluster #2 is the only one which can be observed in non-TNBC tumors (shown in dashed lines in the upper triangle). Panel (b) is similar to panel (a) but shows correlations in TNBC tumors in its upper triangle. Note that cluster #2 is also largely preserved. Panel (c) compares TNBC and non-TNBC tumors. Out of 4 gene clusters identified for Wnt component genes in TNBC, 3 (#A, #B and #C) are somewhat paralleled in non-TNBC (dashed lines).
