Figure 1
From: MicroRNA expression profile of human advanced coronary atherosclerotic plaques

RT-qPCR-analysis of expression of miRs in human coronary atherosclerotic plaques (CAP) from patients with acute coronary syndromes (ACS) (n = 12), who underwent percutaneous directional coronary atherectomy (DCA) and from unaffected specimen from the internal mammary artery (IMA) as a control group (n = 14): (A) miRs down-regulated expression in CAP vs. control group (IMA), (B) miRs up-regulate expression in CAP vs. control group (IMA), and (C) miR whose expression did not alter. Snord44 was used as reference gene for normalization and the relative miRNA expression was calculated using the 2−ΔΔCT method. Data are presented as box plot with median (25th/75th percentiles) log ratios (Tukey) and compared using Kruskal-Wallis test followed by Dunn’s corrections for multiple comparisons. The alpha value was 0.05 and the adjusted p-values compared to control group are presented in each graph.