Figure 5

The reduced visualization of the detected motifs in the PD-GRN network. Motifs A and B and associated functional homogeneity plots depicting the cumulative distribution of GO functional semantic scores of gene pairs of co-regulated genes in the examined motif (red) versus randomly selected genes (black). The p-value was calculated using the Kolmogorov-Smirnov test. The network motifs were visualized using the Cytoscape tool.