Table 2 Morphological changes induced by Pb2+ on RBC.

From: Pb(II) Induces Scramblase Activation and Ceramide-Domain Generation in Red Blood Cells

Pb2+ Time

Pre-treatment

Diameter (µm)

Maximum Thickness (µm)

Morphology

0

None

9.19 ± 0.65

1.44 ± 0.12

Doughnut

20 min

None

8.40 ± 0.46

1.10 ± 0.11

Flat/Spiked

1 h

None

7.15 ± 0.64

2.74 ± 0.28

Spherical

0

Clotrimazole

9.32 ± 0.46

1.44 ± 0.09

Doughnut

20 min

Clotrimazole

9.35 ± 0.45

1.41 ± 0.07

Doughnut

15 h

Clotrimazole

8.67 ± 0.21

1.21 ± 0.12

Doughnut/Flat

0

βMCD

8.74 ± 0.51

2.12 ± 0.16

Doughnut

40 min

βMCD

6.94 ± 0.44

3.05 ± 0.45

Spherical

  1. Overview of the AFM data. Mean values ± S.D. (n = 50–200 cells, through 3 different experiments).