Table 3 Association between factor XIII (FXIII) levels before thrombolysis and the severity and etiology of the stroke.

From: Low factor XIII levels after intravenous thrombolysis predict short-term mortality in ischemic stroke patients

Severity of Stroke

 

NIHSS 0–5 (n = 37)

NIHSS 6–10 (n = 48)

NIHSS 11–15 (n = 21)

NIHSS > 15 (n = 23)

P-value*

FXIII activity (%)

129.7 ± 39.9

126.2 ± 39.6

125.6 ± 26.4

120.5 ± 32.3

0.808

FXIII-A2B2 (mg/l)

23.1 ± 7.8

22.6 ± 9.5

21.8 ± 5.0

21.1 ± 5.4

0.805

Etiology of Stroke

 

Small vessel infarcts (n = 14)

Large vessel thrombosis (n = 49)

Cardio-embolic (n = 27)

P-value small vessel infarcts vs. cardioembolic

P -value atherothrombotic vs. cardioembolic

FXIII activity (%)

145.6 ± 33.4

130.5 ± 38.3

117.5 ± 24.0

0.038

0.012

FXIII-A2B2 (mg/l)

25.5 ± 7.4

22.8 ± 8.3

20.8 ± 4.8

0.160

0.058

  1. Results are expressed as mean ± standard deviation. NIHSS, National Institute of Health Stroke Scale; n, number of patients. *Univariate analysis (ANOVA); ANOVA with Bonferroni post hoc test; atherothrombotic: small vessel infarcts + large vessel thrombosis.